Rhabdomyolysis-Induced Acute Kidney Injury Under Hypoxia and Deprivation of Food and Water

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Rhabdomyolysis-induced acute kidney injury under hypoxia and deprivation of food and water.

BACKGROUND To investigate the renal pathophysiologyin rhabdomyolysis-induced acute kidney injury (AKI) in rats under hypoxia and deprivation of food and water (HDFW), thus broadening the knowledge about rhabdomyolysis-induced AKI in massive earthquake. METHODS Male Wistar rats weighing 200-230g were randomized into control, rhabdomyolysis (R), HDFW and rhabdomyolysis in combination with HDFW ...

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Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury.

BACKGROUND Indirect evidence suggests that hypoxia contributes to the pathophysiology of rhabdomyolysis-induced acute kidney injury (AKI). However, the cellular location and kinetics of hypoxia, as well as potential hypoxia adaptation are unclear. METHODS Rhabdomyolysis was induced in rats by IM glycerol (GLY) injection, which largely recapitulates the full clinical syndrome. Additional rats ...

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Rhabdomyolysis and acute kidney injury.

From the Muscle Research Unit, Depart­ ment of Internal Medicine (X.B., J.M.G.), and the Department of Nephrology (E.P.), Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Univer­ sity of Barcelona, Barcelona. Address re­ print requests to Dr. Grau at the Muscle Research Unit, Department of Internal Medicine, Hospital Clínic, Institut d’Inves­ tigacions Biomèdiques Augu...

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Adolescent with Hypothyroidism Induced Rhabdomyolysis and Acute Kidney Injury

Rhabdomyolysis is a potentially life-threatening syndrome characterized by muscle necrosis and the release of intracellular muscle contents into the circulation. The etiology of rhabdomyolysis can be classified into traumatic and nontraumatic causes. The latter is associated with alcohol and drug abuse, seizures, strenuous exercise, muscle hypoperfusion, hyperthermia, electrolyte disturbances, ...

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Wasp stings (Vespa affinis) induced acute kidney injury following rhabdomyolysis in a 25-year-old woman.

 Wasp sting is a relatively common arthropod assault. This usually results in pain and mild allergic reactions, but sometimes may cause severe systemic reaction and multiorgan dysfunction including rhabdomyolysis, hemolysis, coagulopathy, hepatic, renal and cardiac complications. Along with several other pathomechanisms, rhabdomyolysis is a distinguished cause of acute kidney injury (AKI) in pa...

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ژورنال

عنوان ژورنال: Kidney and Blood Pressure Research

سال: 2013

ISSN: 1423-0143,1420-4096

DOI: 10.1159/000350154